Gilly, Arthur; Suveges, Daniel; Kuchenbaecker, Karoline; Pollard, Martin; Southam, Lorraine; Hatzikotoulas, Konstantinos; Farmaki, Aliki-Eleni; Bjørnland, Thea; Waples, Ryan; Appel, Emil; Casalone, Elisabetta; Melloni, Giorgio; Kilian, Britt; Rayner, William; Ntalla, Ioanna; Kundu, Kousik; Walter, Klaudia; Danesh, John; Butterworth, Adam; Barroso, Ines; Tsafantakis, Emmanouil; Dedoussis, George; Moltke, Ida; Zeggini, Eleftheria (Journal article; Peer reviewed, 2018)
The role of rare variants in complex traits remains uncharted. Here, we conduct deep whole genome sequencing of 1457 individuals from an isolated population, and test for rare variant burdens across six cardiometabolic ...